Adaptation to an Amoeba Host Leads to Pseudomonas aeruginosa Isolates with Attenuated Virulence-Reference-Cited by-同舟云学术

Adaptation to an Amoeba Host Leads to Pseudomonas aeruginosa Isolates with Attenuated Virulence

Published:2022-03-08 Issue:5 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Leong Wai¹,Poh Wee Han¹,Williams Jonathan²³,Lutz Carla¹,Hoque M. Mozammel⁴^ORCID,Poh Yan Hong¹,Yee Benny Yeo Ken¹⁵,Chua Cliff¹⁵,Givskov Michael¹⁶,Sanderson-Smith Martina²³^ORCID,Rice Scott A.¹⁴⁵^ORCID,McDougald Diane¹⁴^ORCID

Affiliation:

1. Singapore Centre for Environmental Life Science Engineering, Nanyang Technological University, Singapore

2. Illawarra Health and Medical Research Institute, Wollongong, Australia

3. School of Chemistry and Molecular Biosciences, Molecular Horizons, University of Wollongong, Wollongong, Australia

4. The iThree Institute, University of Technology Sydney, Sydney, Australia

5. School of Biological Sciences, Nanyang Technological University, Singapore

6. Costerton Biofilm Centre, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute infections in plants and animals, including humans, and chronic infections in immunocompromised and cystic fibrosis patients. This bacterium is commonly found in soils and water, where bacteria are constantly under threat of being consumed by bacterial predators, e.g., protozoa.

Funder

Australian Research Council

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.02322-21

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