SOS-Independent Pyocin Production in P. aeruginosa Is Induced by XerC Recombinase Deficiency-Reference-Cited by-同舟云学术

SOS-Independent Pyocin Production in P. aeruginosa Is Induced by XerC Recombinase Deficiency

Published:2021-12-21 Issue:6 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Baggett Nina S.¹^ORCID,Bronson Adam S.¹,Cabeen Matthew T.¹^ORCID

Affiliation:

1. Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA

Abstract

Pseudomonas aeruginosa is a versatile and ubiquitous bacterium that frequently infects humans as an opportunistic pathogen. P. aeruginosa competes with other strains within the species by producing killing complexes termed pyocins, which are only known to be induced by cells experiencing DNA damage and the subsequent SOS response. Here, we discovered that strains lacking a recombinase enzyme called XerC strongly produce pyocins independently of the SOS response.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02893-21

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