Topoisomerase I Essentiality, DnaA-Independent Chromosomal Replication, and Transcription-Replication Conflict in Escherichia coli-Reference-Cited by-同舟云学术

Topoisomerase I Essentiality, DnaA-Independent Chromosomal Replication, and Transcription-Replication Conflict in Escherichia coli

Published:2021-08-09 Issue:17 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Leela J. Krishna¹,Raghunathan Nalini¹,Gowrishankar J.¹²^ORCID

Affiliation:

1. Laboratory of Bacterial Genetics, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India

2. Indian Institute of Science Education and Research Mohali, Mohali, SAS Nagar, India

Abstract

In all life forms, double-helical DNA exists in a topologically supercoiled state. The enzymes DNA gyrase and topoisomerase I act, respectively, to introduce and to relax negative DNA supercoils in Escherichia coli .

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00195-21

Reference92 articles.

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2. New Mechanistic and Functional Insights into DNA Topoisomerases

3. DNA Topoisomerases

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5. Supercoiling of the DNA template during transcription.

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