The Mutant β E202K Sliding Clamp Protein Impairs DNA Polymerase III Replication Activity-Reference-Cited by-同舟云学术

The Mutant β E202K Sliding Clamp Protein Impairs DNA Polymerase III Replication Activity

Published:2021-11-05 Issue:23 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Homiski Caleb¹,Scotland Michelle K.¹,Babu Vignesh M. P.¹,Chodavarapu Sundari²,Maul Robert W.¹,Kaguni Jon M.²,Sutton Mark D.¹^ORCID

Affiliation:

1. Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA

2. Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA

Abstract

The β clamp plays critically important roles in managing the actions of multiple proteins at the replication fork. However, we lack a molecular understanding of both how the clamp interacts with these different partners and the mechanisms by which it manages their respective actions.

Funder

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00303-21

Reference78 articles.

1. Structure of a Sliding Clamp on DNA

2. Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

3. Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme

4. Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, Ellenberger T. 2006. DNA repair and mutagenesis, 2nd ed. American Society of Microbiology, Washington DC.

5. A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX4 forms DnaX3deltadelta'

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