Microcin H47, a chromosome-encoded microcin antibiotic of Escherichia coli

Author:

Laviña M1,Gaggero C1,Moreno F1

Affiliation:

1. Instituto de Investigaciones Biológicas Clemente Estable Ministerio de Educación y Cultura, Montevideo, Uruguay.

Abstract

Microcin H47 (MccH47) is a novel microcin antibiotic produced by a natural Escherichia coli isolate. In contrast to all the other colicins and microcins examined to date, which are plasmid encoded, the genes for MccH47 synthesis and immunity are located on the chromosome. These genetic determinants were cloned and shown to extend over a continuous DNA region of ca. 10 kb.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference19 articles.

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