The Molecular Basis of Acinetobacter baumannii Cadmium Toxicity and Resistance

Author:

Alquethamy Saleh F.12,Adams Felise G.3ORCID,Maharjan Ram4,Delgado Natasha N.4,Zang Maoge3,Ganio Katherine2,Paton James C.1ORCID,Hassan Karl A.5ORCID,Paulsen Ian T.4ORCID,McDevitt Christopher A.12ORCID,Cain Amy K.4,Eijkelkamp Bart A.3ORCID

Affiliation:

1. Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia

2. Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia

3. Molecular Sciences & Technology, College of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia

4. ARC Centre of Excellence in Synthetic Biology, Department of Molecular Sciences, Macquarie University, Sydney, New South Wales, Australia

5. School of Environmental and Life Sciences, University of Newcastle, Callaghan, New South Wales, Australia

Abstract

Cadmium toxicity is a widespread problem, yet the interaction of this heavy metal with biological systems is poorly understood. Some microbes have evolved traits to proactively counteract cadmium toxicity, including Acinetobacter baumannii , which is notorious for persisting in harsh environments.

Funder

Australian research council

Australian Research Council

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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