In Vitro Activities of New Quinolones and Oxazolidinones against Actinomadura madurae-Reference-Cited by-同舟云学术

In Vitro Activities of New Quinolones and Oxazolidinones against Actinomadura madurae

Published:2004-03 Issue:3 Volume:48 Page:1037-1039
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Vera-Cabrera Lucio¹,Ochoa-Felix Elsa Y.¹²,Gonzalez Gloria²,Tijerina Rolando²,Choi Sung H.³,Welsh Oliverio¹

Affiliation:

1. Laboratorio Interdisciplinario de Investigación Dermatológica, Servicio de Dermatología, Hospital Universitario

2. Research Laboratory, Dong-A Pharmaceutical Company, Limited, Yongin, Korea

3. Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México

Abstract

ABSTRACT In this work, we studied the in vitro sensitivity of 24 strains of Actinomadura madurae to a new oxazolidinone (DA-7867), gatifloxacin, moxifloxacin, and garenoxacin by using a broth microdilution method. We observed that the A. madurae strains had a high level of sensitivity to all the antimicrobials tested. The most active drug was DA-7867, with a MIC at which 90% of the strains are inhibited (MIC 90 ) of 0.125 μg/ml and a MIC 50 of 0.06 μg/ml.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.3.1037-1039.2004

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