Affiliation:
1. Bacterial Pathogenesis Research Group, Department of Microbiology, Monash University, Victoria 3800, Australia
Abstract
ABSTRACT
The
Shigella
resistance locus (SRL) pathogenicity island (PAI) in
Shigella
spp. mediates resistance to streptomycin, ampicillin, chloramphenicol, and tetracycline. It can be excised from the chromosome via site-specific recombination mediated by the P4-related
int
gene. Here, we show that SRL PAI
attP
is capable of RecA-independent, site-specific,
int
-mediated integration into two bacterial tRNA
attB
sites.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
16 articles.
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