Broad-Range 16S rRNA PCR with Cerebrospinal Fluid May Be Unreliable for Management of Postoperative Aseptic Meningitis-Reference-Cited by-同舟云学术

Broad-Range 16S rRNA PCR with Cerebrospinal Fluid May Be Unreliable for Management of Postoperative Aseptic Meningitis

Published:2010-09 Issue:9 Volume:48 Page:3331-3333
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Zarrouk Virginie¹,Leflon-Guibout Véronique²,Robineaux Sébastien¹,Kalamarides Michel³,Nicolas-Chanoine Marie-Hélène²,Sterkers Olivier⁴,Fantin Bruno¹

Affiliation:

1. Department of Internal Medicine

2. Department of Microbiology

3. Department of Neurosurgery

4. Department of ENT, Assistance Publique-Hôpitaux de Paris, Hôpital Beaujon, University Paris-Diderot, F-92110 Clichy, France

Abstract

ABSTRACT We previously demonstrated that discontinuing presumptive antibiotic treatment in cases of negative conventional cultures is safe and effective for patients with postoperative aseptic meningitis (PAM). Here, we prospectively investigated 32 patients with postoperative meningitis. All 26 patients with PAM diagnosed on the basis of conventional cultures demonstrated negative 16S rRNA PCR results. Our results suggest that the PCR technique does not change PAM management.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00008-10

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