Protection against Ehrlichia equi is conferred by prior infection with the human granulocytotropic Ehrlichia (HGE agent)

Author:

Barlough J E1,Madigan J E1,DeRock E1,Dumler J S1,Bakken J S1

Affiliation:

1. Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.

Abstract

A Thoroughbred filly that developed clinical signs of equine granulocytic ehrlichiosis following inoculation with the human granulocytotropic ehrlichia was shown to be resistant to challenge with Ehrlichia equi, a closely related agent. This result further substantiates the close and potentially conspecific relationship between these two granulocytotropic ehrlichiae.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference16 articles.

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2. Human granulocytic ehrlichiosis in the upper midwest United States. A new species emerging;Bakken J. S.;JAMA,1994

3. Barlough J. E. J. E. Madigan E. DeRock and L. Bigornia. Nested polymerase chain reaction for detection of Ehrlichia equi genomic DNA in horses and ticks (Ixodes pacificus). Vet. Parasitol. in press.

4. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease;Chen S.;J. Clin. Microbiol.,1994

5. Serologic cross-reactions among Ehrlichia equi, Ehrlichia phagocytophila, and human granulocytic ehrlichia;Dumler J. S.;J. Clin. Microbiol.,1995

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