Regions of Mouse Mammary Tumor Virus Superantigen Involved in Interaction with the Major Histocompatibility Complex Class II I-A Molecule-Reference-Cited by-同舟云学术

Regions of Mouse Mammary Tumor Virus Superantigen Involved in Interaction with the Major Histocompatibility Complex Class II I-A Molecule

Published:2002-11 Issue:21 Volume:76 Page:11172-11175
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wirth Susanne¹,Vessaz Annelyse¹,Krummenacher Claude¹,Baribaud Frédéric¹,Acha-Orbea Hans²³,Diggelmann Heidi¹

Affiliation:

1. Institute of Microbiology, University of Lausanne, CH-1011 Lausanne

2. Institute of Biochemistry, University of Lausanne

3. Ludwig Institute for Cancer Research, Lausanne Branch, CH-1066 Epalinges, Switzerland

Abstract

ABSTRACT To study the major histocompatibility complex class II I-E dependence of mouse mammary tumor virus (MMTV) superantigens, we constructed hybrids between the I-E-dependent MMTV(GR) and the I-E-independent mtv - 7 superantigens and tested them in vivo. Our results suggest that, although the C-terminal third mediates I-A interaction, additional binding sites are located elsewhere in the superantigen.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.76.21.11172-11175.2002

Reference11 articles.

1. Acha-Orbea, H., R. M. Zinkernagel, and H. Hengartner. 1985. Cytotoxic T cell clone-specific monoclonal antibodies used to select clonotypic antigen-specific cytotoxic T cells. Eur. J. Immunol. 15 : 31-36.

2. Identification of Key Amino Acids of the Mouse Mammary Tumor Virus Superantigen Involved in the Specific Interaction with T-Cell Receptor V β Domains

3. Blochlinger, K., and H. Diggelmann. 1992. Expression of the mouse mammary tumor virus ORF gene in cultured cells. Int. Rev. Immunol. 8 : 337-355.

4. Hsu, P.-N., P. Wolf Bryant, N. Sutkowski, B. McLellan, H. L. Ploegh, and B. T. Huber. 2001. Association of mouse mammary tumor virus superantigen with MHC class II during biosynthesis. J. Immunol. 166 : 3309-3314.

5. Krummenacher, C., and H. Diggelmann. 1993. The mouse mammary tumor virus long terminal repeat encodes a 47 kDa glycoprotein with a short half-life in mammalian cells. Mol. Immunol. 30 : 1151-1157.

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