Affiliation:
1. WHO Collaborating Center for Tropical Diseases, Sealy Center for Vaccine Development, and Department of Pathology, The University of Texas Medical Branch, Galveston, Texas 77555-0609
Abstract
ABSTRACT
Using a panel of neutralizing monoclonal antibodies, we have mapped epitopes in domain III of the envelope protein of the New York strain of West Nile virus. The ability of monoclonal antibodies that recognize these epitopes to neutralize virus appeared to differ between lineage I and II West Nile virus strains, and epitopes were located on the upper surface of domain III at residues E307, E330, and E332.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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