Induction of Telithromycin Resistance by Erythromycin in Isolates of Macrolide-Resistant Staphylococcus spp-Reference-Cited by-同舟云学术

Induction of Telithromycin Resistance by Erythromycin in Isolates of Macrolide-Resistant Staphylococcus spp

Published:2005-07 Issue:7 Volume:49 Page:3059-3061
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Davis Kepler A.¹,Crawford Sharon A.²,Fiebelkorn Kristin R.²,Jorgensen James H.²

Affiliation:

1. Infectious Diseases Service, Department of Medicine, Brooke Army Medical Center, Ft. Sam Houston, Texas 78234

2. Department of Pathology, The University of Texas Health Science Center, San Antonio, Texas 78229

Abstract

ABSTRACT Staphylococcal isolates were examined for possible macrolide-inducible resistance to telithromycin. All macrolide-resistant isolates demonstrated telithromycin D-shaped zones. This result did not discriminate between resistance due to an efflux mechanism ( msrA ) or a ribosomal target modification ( ermA or ermC ). Inducible telithromycin resistance in staphylococci does not appear to be analogous to inducible clindamycin resistance.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.7.3059-3061.2005

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