InVitro Antibacterial Activity of DX-619, a Novel Des-Fluoro(6) Quinolone

Author:

Fujikawa Katsuko1,Chiba Megumi1,Tanaka Mayumi1,Sato Kenichi1

Affiliation:

1. New Product Research Laboratories I, Daiichi Pharmaceutical Co. Ltd., Tokyo, Japan

Abstract

ABSTRACT The in vitro activities of DX-619, des-fluoro(6) quinolone, against 1,208 clinical isolates were examined. DX-619 was particularly potent against staphylococci, including ciprofloxacin- and methicillin-resistant strains; the MIC at which 90% of the strains tested were inhibited was 0.5 μg/ml. In addition, DX-619 was also active against gram-negative bacteria.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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