Affiliation:
1. Departments of Medicine and Pathology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901-0019
Abstract
ABSTRACT
Although imipenem has in vitro activity against
Enterococcus faecalis
and Food and Drug Administration-approved indications for treatment of infections caused by this microorganism, there are no NCCLS guidelines for susceptibility testing of imipenem versus enterococci. Therefore, the in vitro activities of penicillin, ampicillin, imipenem, and vancomycin against 201 blood isolates of
E. faecalis
and 24 blood isolates of
Enterococcus faecium
were compared. The susceptibility of isolates to penicillin or ampicillin accurately predicted the in vitro activity of imipenem. Since the susceptibility of enterococci to imipenem can be predicted by the results obtained by testing of penicillin or ampicillin, testing of imipenem by clinical laboratories probably is not necessary.
Publisher
American Society for Microbiology
Cited by
31 articles.
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