Comparison of Serogroup W-135 Meningococci Isolated in Sweden during a 23-Year Period and Those Associated with a Recent Hajj Pilgrimage

Author:

Mölling Paula1,Bäckman Anders1,Olcén Per1,Fredlund Hans12

Affiliation:

1. National Reference Laboratory for Pathogenic Neisseria1 and

2. Unit for Infectious Disease Control,2 Department of Clinical Microbiology & Immunology, Örebro Medical Centre Hospital,Örebro, Sweden

Abstract

ABSTRACT An outbreak of serogroup W-135 meningococcal disease was reported among pilgrims returning from the annual hajj (pilgrimage to Mecca) in mid-March 2000. Molecular characterization was used to investigate the similarity of the hajj-associated W-135 strains with those isolated in Sweden during a 23-year period (1978 to 2000). The same hajj-associated genosubtype, genosubtype P1.5,2,36b, has been documented in Sweden since 1979, while pulsed-field gel electrophoresis and the sulfadiazine resistance of the W-135 isolates indicated that the outbreak was probably due to a new clone of W-135 meningococci.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference19 articles.

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3. Immunological investigations of meningococcal disease. III. Brevity of group C acquisition prior to disease occurrence;Edwards E. A.;Scand. J. Infect. Dis.,1977

4. Infectious diseases associated with complement deficiencies

5. Serogroup W-135 meningococcal disease among travelers returning from Saudi Arabia—United States;Fine A.;Morb. Mortal. Wkly. Rep.,2000

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