Affiliation:
1. Department of Biology, Georgetown University, Washington, DC, USA
Abstract
ABSTRACT
For years, studies of the immune response to
Giardia lamblia
infection focused on the production of IgA by infected hosts and antigenic variation by the parasite to escape destruction by this IgA. A new study by Hanevik and colleagues (C. S. Saghaug, S. Sørnes, D. Peirasmaki, S. Svärd, N. Langeland, and K. Hanevik, Clin Vaccine Immunol 23:11–18, 2016,
http://dx.doi.org/10.1128/CVI.00419-15
) highlights the emerging role of interleukin-17 (IL-17) in immunity to this parasite. Along with recent studies of
Giardia
infections of animals, this work shows that IL-17 appears to be essential for the control of these infections and to be a key factor linking cellular and humoral immune responses.
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
Publisher
American Society for Microbiology
Subject
Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy
Cited by
20 articles.
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