Effects of F171 Mutations in the 6′- N -Acetyltransferase Type Ib [AAC(6′)-Ib] Enzyme on Susceptibility to Aminoglycosides-Reference-Cited by-同舟云学术

Effects of F171 Mutations in the 6′- N -Acetyltransferase Type Ib [AAC(6′)-Ib] Enzyme on Susceptibility to Aminoglycosides

Published:1999-11 Issue:11 Volume:43 Page:2811-2812
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chavideh Ramona¹,Sholly Steven¹,Panaite Doina¹,Tolmasky Marcelo E.¹

Affiliation:

1. Institute of Molecular Biology and Nutrition, Department of Biological Science, School of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California 92834-6850

Abstract

ABSTRACT Substitutions at position F171 of 6′- N -acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.11.2811

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