High-Level Aminoglycoside Resistance in the Beta-Hemolytic Group G Streptococcus Isolate BM2721-Reference-Cited by-同舟云学术

High-Level Aminoglycoside Resistance in the Beta-Hemolytic Group G Streptococcus Isolate BM2721

Published:1999-12 Issue:12 Volume:43 Page:3008-3010
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Galimand Marc¹,Lambert Thierry²,Gerbaud Guy¹,Courvalin Patrice¹

Affiliation:

1. Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15,1 and

2. Centre d’Etudes Pharmaceutiques, 92296 Châtenay-Malabry,2 France

Abstract

ABSTRACT The beta-hemolytic group G Streptococcus clinical isolate BM2721 was resistant to high levels of aminoglycosides by synthesis of AAC(6′)-APH(2"), APH(3′)-III, and ANT(6) modifying enzymes. The corresponding genes were found to be adjacent as the result of a recombination event between Tn 4001 and Tn 5405 , two transposons originating in staphylococci.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.12.3008

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