Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species-Reference-Cited by-同舟云学术

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

Published:2010-12 Issue:23 Volume:76 Page:7881-7884
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Topp Shana¹²,Reynoso Colleen M. K.¹,Seeliger Jessica C.²,Goldlust Ian S.¹,Desai Shawn K.¹,Murat Dorothée³,Shen Aimee⁴,Puri Aaron W.⁴,Komeili Arash³,Bertozzi Carolyn R.²⁵⁶,Scott June R.⁷,Gallivan Justin P.¹

Affiliation:

1. Department of Chemistry and the Center for Fundamental and Applied Molecular Evolution, Emory University, Atlanta, Georgia 30322

2. Departments of Chemistry

3. Plant and Microbial Biology

4. Department of Pathology, Stanford University School of Medicine, Stanford, California 94305

5. Molecular and Cell Biology

6. Howard Hughes Medical Institute, University of California, Berkeley, California 94720

7. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322

Abstract

ABSTRACT We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01537-10

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