1. Second Department of Internal Medicine, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata City, Yamagata 990-9585,1
2. Gastrointestinal Division, Hamamatsu Medical Center, Hamamatsu City, Shizuoka 432-8002,2 and
3. Department of Food and Nutritional Sciences, University of Shizuoka Hamamatsu College, 3-2-3 Nunohashi, Hamamatsu City, Shizuoka 432-8012,3 Japan