Detection and Isolation of Campylobacter Species Other than C. jejuni from Children with Crohn's Disease

Author:

Zhang Li1,Man Si Ming1,Day Andrew S.23,Leach Steven T.3,Lemberg Daniel A.2,Dutt Shoma4,Stormon Michael4,Otley Anthony5,O'Loughlin Edward V.4,Magoffin Annabel4,Ng Patrick H. Y.1,Mitchell Hazel1

Affiliation:

1. The School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia

2. Department of Gastroenterology, Sydney Children's Hospital, Sydney, Australia

3. School of Women's and Children's Health, University of New South Wales, Sydney, Australia

4. Department of Gastroenterology, Children's Hospital at Westmead, Sydney, Australia

5. IWK Health Centre, Division of Gastroenterology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

Abstract

ABSTRACT The presence of Campylobacter species other than Campylobacter jejuni and antibodies to Campylobacter concisus in children were investigated. A significantly greater presence of C. concisus and higher levels of antibodies to C. concisus were detected in children with Crohn's disease (CD) than in controls. Campylobacter species other than C. jejuni were isolated from intestinal biopsy specimens of children with CD.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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