A Direct Comparison of Enhanced Saliva to Nasopharyngeal Swab for the Detection of SARS-CoV-2 in Symptomatic Patients-Reference-Cited by-同舟云学术

A Direct Comparison of Enhanced Saliva to Nasopharyngeal Swab for the Detection of SARS-CoV-2 in Symptomatic Patients

Published:2020-10-21 Issue:11 Volume:58 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Procop Gary W.¹^ORCID,Shrestha Nabin K.²^ORCID,Vogel Sherilynn¹,Van Sickle Kelly¹,Harrington Susan¹,Rhoads Daniel D.¹,Rubin Brian P.¹,Terpeluk Paul³

Affiliation:

1. Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA

2. Department of Infectious Diseases, Cleveland Clinic, Cleveland, Ohio, USA

3. Department of Internal Medicine and Geriatrics, Cleveland Clinic, Cleveland, Ohio, USA

Abstract

The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in shortages of nasopharyngeal swabs (NPS) and viral transport media, necessitating the search for alternate diagnostic specimens, such as saliva. We directly compared matched saliva and NPS specimens from symptomatic patients suspected of having COVID-19. An enhanced saliva specimen (i.e., strong sniff, elicited cough, and collection of saliva/secretions) was collected without transport medium prior to collection of NPS from 224 patients with symptoms deemed consistent with COVID-19.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01946-20

Reference20 articles.

1. The SARS-CoV-2 Outbreak: Diagnosis, Infection Prevention, and Public Perception

2. Laboratories and Pandemic Preparedness

3. Self-Collected Oral Fluid and Nasal Swabs Demonstrate Comparable Sensitivity to Clinician Collected Nasopharyngeal Swabs for Covid-19 Detection

4. A combined oropharyngeal/nares swab is a suitable alternative to nasopharyngeal swabs for the detection of SARS-CoV-2

5. Posterior Oropharyngeal Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Cited by 86 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Clinical and laboratory characteristics of patients hospitalized with severe COVID-19 in New Orleans, August 2020 to September 2021;Scientific Reports;2024-03-19

2. Clinical usefulness of the “GeneSoC^® SARS-CoV-2 N2 Detection Kit”;Journal of Laboratory Medicine;2024-02-28

3. Salivary Specimen in COVID-19 Testing for Dental Settings: A Meta-Analysis Comparing Saliva, Nasopharyngeal and Serum Specimens;Annals of Dental Specialty;2024

4. The Infectious Diseases Society of America Guidelines on the Diagnosis of Coronavirus Disease 2019 (COVID-19): Molecular Diagnostic Testing;Clinical Infectious Diseases;2023-12-19

5. Double-Negative Results Matter: A Reevaluation of Sensitivities for Detecting SARS-CoV-2 Infection Using Saliva Versus Nasopharyngeal Swabs;American Journal of Epidemiology;2023-11-03