A Stewardship Approach To Optimize Antimicrobial Therapy through Use of a Rapid Microarray Assay on Blood Cultures Positive for Gram-Negative Bacteria-Reference-Cited by-同舟云学术

A Stewardship Approach To Optimize Antimicrobial Therapy through Use of a Rapid Microarray Assay on Blood Cultures Positive for Gram-Negative Bacteria

Published:2015-11 Issue:11 Volume:53 Page:3627-3629
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Sothoron Conner¹,Ferreira Jason¹,Guzman Nilmarie²,Aldridge Petra³,McCarter Yvette S.⁴,Jankowski Christopher A.¹

Affiliation:

1. Department of Pharmacy, University of Florida Health Jacksonville, Jacksonville, Florida, USA

2. Department of Medicine, Division of Infectious Disease, University of Florida Health Jacksonville, Jacksonville, Florida, USA

3. Center for Health Equity and Quality Research, Jacksonville, Florida, USA

4. Department of Pathology and Laboratory Medicine, University of Florida College of Medicine, Jacksonville, Florida, USA

Abstract

ABSTRACT A Gram-negative (GN) blood culture microarray assay with an antimicrobial stewardship program (ASP) intervention was evaluated in 126 patients with GN bacteremia. The median time to optimal therapy was shorter in the postintervention group than in the preintervention group (49.3 h versus 38.5 h, respectively; P = 0.0199). ASP can utilize microarray technology to decrease the time to optimal antimicrobial therapy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02161-15

Reference18 articles.

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4. Evaluation of an Automated Rapid Diagnostic Assay for Detection of Gram-Negative Bacteria and Their Drug-Resistance Genes in Positive Blood Cultures

5. Identification of Gram-Negative Bacteria and Genetic Resistance Determinants from Positive Blood Culture Broths by Use of the Verigene Gram-Negative Blood Culture Multiplex Microarray-Based Molecular Assay

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