Tetramerization of Phosphoprotein Is Essential for Respiratory Syncytial Virus Budding while Its N-Terminal Region Mediates Direct Interactions with the Matrix Protein-Reference-Cited by-同舟云学术

Tetramerization of Phosphoprotein Is Essential for Respiratory Syncytial Virus Budding while Its N-Terminal Region Mediates Direct Interactions with the Matrix Protein

Published:2021-03-10 Issue:7 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Bajorek Monika¹^ORCID,Galloux Marie¹^ORCID,Richard Charles-Adrien¹,Szekely Or²^ORCID,Rosenzweig Rina²^ORCID,Sizun Christina³,Eleouet Jean-Francois¹

Affiliation:

1. Université Paris-Saclay, INRAE, UVSQ, VIM, Jouy-en-Josas, France

2. Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

3. Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France

Abstract

Human respiratory syncytial virus (RSV) is the leading cause of infantile bronchiolitis in the developed world and of childhood deaths in resource-poor settings. It is a major unmet target for vaccines and antiviral drugs.

Funder

Agence Nationale de la Recherche

Weizmann Institute of Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02217-20

Reference58 articles.

1. Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study

2. Épidémiologie de la bronchiolite du nourrisson en France