Inhibitory effect of flavin mononucleotide on the hemolysis of rabbit erythrocytes by staphylococcal alpha-toxin

Author:

Kato I,Sakoda K,Saito M,Suzuki Y,Watanabe M

Abstract

Flavin mononucleotide diminished the hemolytic action of staphylococcal alpha-toxin on rabbit erythrocytes by competitive inhibition, probably by its interaction with the alpha-toxin binding sites on the cell membrane.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference7 articles.

1. Arbuthnott J. P. 1970. Staphylococcal alpha-toxin p. 189-236. In T. C. Montie S. Kadis and S. J. Ajl (ed.) Microbial toxins vol. 3. Academic Press Inc. New York.

2. Interactions between membranes and cytolytic bacterial toxins;Bernheimer A. W.;Biochim. Biophys. Acta,1974

3. Isolation and composition of staphylococcal alpha-toxin;Bernheimer A. W.;J. Gen. Microbiol.,1963

4. Biological properties of staphylococcal alpha-toxin;Cassidy P.;Biochim. Biophys. Acta,1974

5. Effect of diphtheria toxin on Iysosome activity of leukocytes and Ehrlich ascites tumor cells;Kato I.;Jpn. J. Exp. Med.,1970

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1. ALPHA-TOXIN OF STAPHYLOCOCCUS-AUREUS;MICROBIOL REV;1991

2. Alpha-toxin of Staphylococcus aureus;Microbiological Reviews;1991-12

3. Binding of 125I-Alpha Toxin of Staphylococcus Aureus to Erythrocytes;Journal of Medical Microbiology;1984-10-01

4. Crystallization and Some Properties of Leukocidin fromPseudomonas aeruginosa;Microbiology and Immunology;1983-07

5. Toxins of staphylococcus aureus;Pharmacology & Therapeutics;1982

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