Potential Secondary Pathogenic Role for Bovine Herpesvirus 4-Reference-Cited by-同舟云学术

Potential Secondary Pathogenic Role for Bovine Herpesvirus 4

Published:2005-07 Issue:7 Volume:43 Page:3421-3426
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Donofrio Gaetano¹,Cavirani Sandro¹,van Santen Vicky²,Flammini Cesidio Filippo¹

Affiliation:

1. Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali Facoltà di Medicina Veterinaria, via del Taglio 8, 43100 Parma, Italy

2. Department of Pathobiology, 264 Greene Hall, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849-5519

Abstract

ABSTRACT Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Previous studies have demonstrated that macrophages can harbor persistent BoHV-4. We found that the addition of prostaglandin E2 (PGE2) to bovine macrophage cells persistently infected with BoHV-4 increases viral replication. Because opportunistic infection can increase PGE2 production, we propose a link between opportunistic infection, PGE2 production, and BoHV-4 replication.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.43.7.3421-3426.2005

Reference22 articles.

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3. Donofrio, G., and V. L. van Santen. 2001. A bovine macrophage cell line supports bovine herpesvirus 4 persistent infection. J. Gen. Virol.82:1181-1185.

4. Detection of Bovine Herpesvirus 4 (BoHV-4) DNA in the Cell Fraction of Milk of Dairy Cattle with History of BoHV-4 Infection

5. Donofrio, G., S. Cavirani, and V. L. van Santen. 2000. Establishment of a cell line persistently infected with bovine herpesvirus 4 using a recombinant virus. J. Gen. Virol.81:1807-1814.

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