Treatment of murine coccidioidal meningitis with SCH39304-Reference-Cited by-同舟云学术

Treatment of murine coccidioidal meningitis with SCH39304

Published:1990-04 Issue:4 Volume:34 Page:663-664
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Defaveri J¹,Sun S H¹,Graybill J R¹

Affiliation:

1. Department of Medicine and Research, Audie L. Murphy Memorial Veterans Hospital, San Antonio, Texas 78284.

Abstract

The triazole SCH39304 was compared with itraconazole and fluconazole for treatment of murine coccidioidal meningitis. Mice were treated for 30 days with 1, 5, 10, or 30 mg of each drug per kg of body weight. Survival and brain tissue counts were measured. At equivalent doses, SCH39304 was more effective than the other triazoles.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.34.4.663

Reference13 articles.

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5. Kelly P. 1980. Coccidioidal meningitis p. 163-193. In D. A. Stevens (ed.) Coccidioidomycosis a text. Plenum Publishing Corp. New York.

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