In vitro activity of 79 antimicrobial agents against Corynebacterium group D2

Author:

García-Rodriguez J A1,García Sánchez J E1,Muñoz Bellido J L1,Nebreda Mayoral T1,García Sánchez E1,García García I1

Affiliation:

1. Department of Microbiology, Hospital Clinico Universitario, Salamanca, Spain.

Abstract

Corynebacterium group D2 (CGD2) is involved in urinary tract infections in patients with underlying predisposing factors. This microorganism is highly resistant to a number of antimicrobial agents. We tested the activities of 79 antimicrobial agents against CGD2. beta-Lactams, aminoglycosides, and macrolides were ineffective. Fluorinated quinolones showed irregular activities, ofloxacin being the most active one. Doxycycline, rifampin, and mainly glycopeptides (vancomycin and teicoplanin) were the most active antibiotics against CGD2.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference16 articles.

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3. Serious infections caused by diphtheroids;Johnson W. D.;Ann. N. Y. Acad. Sci.,1970

4. Corynebacterium group D2. Etude clinique, identification biochemique et sensibilitd aux antibiotiques;Marty N.;Pathol. Biol. (Paris),1988

5. National Committee for Clinical Laboratory Standards. 1990. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically-second edition. Approved standard. NCCLS document M7-A2. National Committee for Clinical Laboratory Standards Villanova Pa.

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