Affiliation:
1. College of Marine Sciences, South China Agricultural University, Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China
2. Southern Marine Science and Engineering Guangdong Laboratory, Zhuhai, China
Abstract
STING has been identified as a critical factor participating in the innate immune response which recruits and phosphorylates TBK1 and IFN regulatory factor 3 (IRF3) to induce IFN production and defend against viral infection. However, viruses also distort the STING-TBK1 pathway to negatively regulate the IFN response and facilitate viral replication.
Funder
National Natural Science Foundation of China
MOST | National Key Research and Development Program of China
China Postdoctoral Science Foundation
GDSTC | Basic and Applied Basic Research Foundation of Guangdong Province
China Agricultural Research System
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Cited by
15 articles.
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