Expression of slime interferes with in vitro detection of host protein receptors of Staphylococcus epidermidis

Author:

Baldassarri L1,Donelli G1,Gelosia A1,Simpson A W1,Christensen G D1

Affiliation:

1. Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Rome, Italy.

Abstract

We hypothesized that slime may mask bacterial molecules important in the attachment of Staphylococcus epidermidis to inanimate surfaces. In support of this hypothesis, we found that slime-negative strains attached significantly better to fibrinogen or fibronectin than the parent strains and exhibited greater surface hydrophobicity. Comparable results were obtained with 53 clinical isolates.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference25 articles.

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5. Christensen G. D. L. Baldassarri and W. A. Simpson. 1994. Colonization of medical devices by coagulase-negative staphylococci p. 45-78. In A. L. Bisno and F. A. Waldvogel (ed.) Infections associated with indwelling medical devices 2nd ed. American Society for Microbiology Washington D.C.

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