Obesity-Related Gut Microbiota Aggravates Alveolar Bone Destruction in Experimental Periodontitis through Elevation of Uric Acid-Reference-Cited by-同舟云学术

Obesity-Related Gut Microbiota Aggravates Alveolar Bone Destruction in Experimental Periodontitis through Elevation of Uric Acid

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Sato Keisuke¹²,Yamazaki Kyoko¹²,Kato Tamotsu³,Nakanishi Yumiko³⁴,Tsuzuno Takahiro¹²,Yokoji-Takeuchi Mai²,Yamada-Hara Miki²,Miura Nobuaki⁵,Okuda Shujiro⁵,Ohno Hiroshi³⁴,Yamazaki Kazuhisa¹³^ORCID

Affiliation:

1. Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan

2. Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan

3. Laboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan

4. Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, Kawasaki, Japan

5. Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan

Abstract

Obesity is an epidemic health issue with a rapid increase worldwide. It increases the risk of various diseases, including periodontal disease, an oral chronic infectious disease.

Funder

MEXT | Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00771-21

Reference47 articles.

1. Periodontal complications with obesity

2. The keystone-pathogen hypothesis