Rid Enhances the 6-Hydroxypseudooxynicotine Dehydrogenase Reaction in Nicotine Degradation by Agrobacterium tumefaciens S33

Author:

Shang Jinmeng1,Wang Xia1,Zhang Meng1,Wang Rongshui1,Zhang Chengjia1,Huang Haiyan2,Wang Shuning1ORCID

Affiliation:

1. State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, People’s Republic of China

2. Institute of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Science, Jinan, People’s Republic of China

Abstract

Rid is a family of proteins that participate in metabolite damage repair and is widely distributed in different organisms. In this study, we found that Rid-NC, which belongs to the Rid6 subfamily, promoted the 6-hydroxypseudooxynicotine dehydrogenase (Pno) reaction in the hybrid of the pyridine and pyrrolidine pathways for nicotine degradation by Agrobacterium tumefaciens S33.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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