Fatal-Stroke Syndrome Revealing Fungal Cerebral Vasculitis Due to Arthrographis kalrae in an Immunocompetent Patient-Reference-Cited by-同舟云学术

Fatal-Stroke Syndrome Revealing Fungal Cerebral Vasculitis Due to Arthrographis kalrae in an Immunocompetent Patient

Published:2008-09 Issue:9 Volume:46 Page:3152-3155
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Pichon N.¹²,Ajzenberg D.³⁴,Desnos-Ollivier M.⁵,Clavel M.¹²,Gantier J. C.⁵,Labrousse F.⁶

Affiliation:

1. Medical-Surgical Intensive Care Unit, Dupuytren University Hospital, 2 Ave. Martin Luther King, 87042 Limoges Cedex, France

2. Centre Investigation Clinique, Dupuytren University Hospital, Limoges, France

3. Department of Parasitology and Mycology, Dupuytren University Hospital, Limoges, France

4. EA3174-NETEC, Faculty of Medicine, University of Limoges, Limoges, France

5. CNR Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, Paris, France

6. Department of Pathology, Dupuytren University Hospital, Limoges, France

Abstract

ABSTRACT We report an uncommon clinical presentation of a unique case of fatal invasive fungal cerebral vasculitis due to Arthrographis kalrae in a nonimmunocompromised host. The identity of the fungus was determined by morphological characteristics and by analysis of internal transcribed spacer 1 sequences and was confirmed by postmortem examination of the brain tissues. Establishing rapidly the link between the clinical syndromes and the fungal infection of the central nervous system is essential to improve the outcome. As our case has shown, it is more challenging to make a diagnosis of fungal infection when there are no risk factors of immunodeficiency and when the clinical presentation seems uncommon.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00800-08

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