Biochemical properties and purification of metallo-beta-lactamase from Bacteroides fragilis-Reference-Cited by-同舟云学术

Biochemical properties and purification of metallo-beta-lactamase from Bacteroides fragilis

Published:1991-02 Issue:2 Volume:35 Page:371-372
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Bandoh K¹,Muto Y¹,Watanabe K¹,Katoh N¹,Ueno K¹

Affiliation:

1. Institute of Anaerobic Bacteriology, Gifu University School of Medicine, Japan.

Abstract

The beta-lactamase from Bacteroides fragilis GAI-30144 hydrolyzed imipenem, oxyiminocephalosporins, cephamycins, and penicillins. Enzyme activity was inhibited by EDTA. Zinc completely reversed inactivation of the enzyme by EDTA. The molecular mass of purified enzyme was estimated to be 33,000 daltons.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.35.2.371

Reference10 articles.

1. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding;Bradford M.;Anal. Biochem.,1976

2. P-Lactamase-mediated imipenem resistance in Bacteroides fragilis;Cuchural G. J.;Antimicrob. Agents Chemother.,1986

3. Pathogenic anaerobes;Finegold S. M.;Arch. Intern. Med.,1982

4. Biochemical properties of P-lactamase produced by Legionella gormanii;Fujii T.;Antimicrob. Agents Chemother.,1986

5. Macrolide accumulation by Bacteroides fragilis ATCC 25285;Muto Y.;Antimicrob. Agents Chemother.,1989

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Research Progress in Bacteroides Resistance to Carbapenems and Their Resistance Mechanism;Advances in Clinical Medicine;2023

2. Molecular modeling and QM/MM calculation clarify the catalytic mechanism of β-lactamase N1;Journal of Molecular Modeling;2019-04-13

3. Insight into the inhibition mechanism and structure–activity relationship of 2,6-dipicolinic acid and its analogue to New Delhi metallo-β-lactamase-1;Molecular Simulation;2018-12-27

4. Oral Gram-negative anaerobic bacilli as a reservoir of β-lactam resistance genes facilitating infections with multiresistant bacteria;International Journal of Antimicrobial Agents;2015-02

5. First National Survey of Antibiotic Susceptibility of the Bacteroides fragilis Group: Emerging Resistance to Carbapenems in Argentina;Antimicrobial Agents and Chemotherapy;2012-01-09