Reconstruction of Dispersal Patterns of Hypervirulent Meningococcal Strains of Serogroup C:cc11 by Phylogenomic Time Trees

Author:

Lo Presti Alessandra1,Neri Arianna1,Fazio Cecilia1,Vacca Paola1,Ambrosio Luigina1,Grazian Clara23,Liseo Brunero4,Rezza Giovanni1,Maiden Martin Christopher James5ORCID,Stefanelli Paola1

Affiliation:

1. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

2. Department of Economics, Università degli Studi “G. d’Annunzio,” Chieti, Italy

3. School of Mathematics and Statistics, University of New South Wales, Sydney, Australia

4. “Sapienza Università di Roma, MEMOTEF,” Rome, Italy

5. Department of Zoology, University of Oxford, Oxford, United Kingdom

Abstract

Neisseria meningitidis is one of the few commensal bacteria that can even cause large epidemics of invasive meningococcal disease (IMD). N. meningitis serogroup C belonging to the hypervirulent clonal complex 11 (cc11) represents an important public health threat worldwide. We reconstructed the dispersal patterns of hypervirulent meningococcal strains of serogroup C:cc11 by phylogenomic time trees.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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