In vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei-Reference-Cited by-同舟云学术

In vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei

Published:1988-09 Issue:9 Volume:32 Page:1435-1436
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ashdown L R¹

Affiliation:

1. Pathology Laboratory, Commonwealth Department of Community Services and Health, Townsville, Queensland, Australia.

Abstract

Imipenem was highly active and bactericidal against all 100 strains of Pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. The addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. Ciprofloxacin and norfloxacin showed poor activity against test strains.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.32.9.1435

Reference40 articles.

1. P. pseudomallei is known to be a P-lactamase-producing

2. organism (3). When these drugs were combined with the

3. -lactamase-inhibitor clavulanic acid they were consider

4. ably active in vitro. Except for three strains which were

5. totally resistant amoxicillin-clavulanic acid showed inhibi

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