Author:
Norrild B,Ludwig H,Rott R
Abstract
In immunoelectrophoretic analyses one common antigen was demonstrated in antigen preparations from herpes simplex virus types 1- and 2- (HSV-1 and HSV-2), bovine herpes mammillitis (BHM) virus-, and B virus-infected cells solubilized by Triton X-100. The antigen was also demonstrated in solubilized purified HSV-1 and BHM virus. The common antigen was identified as antigen 11 of HSV-1 or HSV-2. Differences were found in the polypeptide composition of the related antigens when isolated from the four different herpesviruses, but a glycopolypeptide with a molecular weight of 125,000 was present in each of the four different antigen preparations, indicating that this polypeptide carried the common antigenic determinants.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference2 articles.
1. Intermediate gel in crossed and in fused rocket immunoelectrophoresis;Axelsen N. H.;Scand. J. Immunol.,1973
2. Bjerrum 0. J. 1977. Immunochemical investigation of membrane proteins. A methodological survey with em- phasis placed on immunoprecipitation in gels. Biochim.
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