Coelacanth SERINC2 Inhibits HIV-1 Infectivity and Is Counteracted by Envelope Glycoprotein from Foamy Virus-Reference-Cited by-同舟云学术

Coelacanth SERINC2 Inhibits HIV-1 Infectivity and Is Counteracted by Envelope Glycoprotein from Foamy Virus

Published:2021-06-10 Issue:13 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ramdas Pavitra¹,Bhardwaj Vipin¹,Singh Aman¹,Vijay Nagarjun²,Chande Ajit¹^ORCID

Affiliation:

1. Molecular Virology Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, India

2. Computational Evolutionary Genomics Lab, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, India

Abstract

SERINC 5 constitutes a critical barrier to the propagation of retroviruses, as highlighted by parallel emergence of anti-SERINC5 activities among distant retroviral lineages. Therefore, understanding the origin and evolution of these host factors will provide key information about virus-host relationships that can be exploited for future drug development.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

The Wellcome Trust DBT India Alliance

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00229-21

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