Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual

Author:

Yan Bingyu1ORCID,Chakravorty Srishti1,Mirabelli Carmen2,Wang Luopin3ORCID,Trujillo-Ochoa Jorge L.4,Chauss Daniel4ORCID,Kumar Dhaneshwar14,Lionakis Michail S.5ORCID,Olson Matthew R.6,Wobus Christiane E.2ORCID,Afzali Behdad4ORCID,Kazemian Majid13ORCID

Affiliation:

1. Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA

2. Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

3. Department of Computer Science, Purdue University, West Lafayette, Indiana, USA

4. Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, USA

5. Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA

6. Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA

Abstract

The pathogenic mechanisms underlying SARS-CoV-2, the virus responsible for COVID-19, are not fully understood. In particular, relatively little is known about the reasons some individuals develop life-threatening or persistent COVID-19.

Funder

Marie Skłodowska-Curie Actions

MICHR Postdoc Translational Scholar Program

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

HHS | NIH | National Institute of General Medical Sciences

Office of Dietary Supplements

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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