Affiliation:
1. Department of Medicine, University of Virginia School of Medicine, Charlottesville 22908.
Abstract
Serum from healthy, nonimmune humans contained immunoglobulin M (IgM) antibodies that agglutinated Leishmania donovani promastigotes, activated complement, and enhanced promastigote ingestion by human monocytes. The findings indicate that IgM antibodies have the capacity to affect the initial interaction of L. donovani promastigotes with human host defenses.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
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