Polymorphisms in Plasmodium falciparum Kelch 13 and P. vivax Kelch 12 Genes in Parasites Collected from Three South Pacific Countries Prior to Extensive Exposure to Artemisinin Combination Therapies

Author:

Gresty Karryn12,Anderson Karen12,Pasay Cielo13,Waters Norman C.4,Cheng Qin12

Affiliation:

1. Drug Resistance and Diagnostic Department, Australian Defence Force Malaria and Infectious Disease Institute, Brisbane, Australia

2. The Army Malaria Institute Laboratory, QIMR-Berghofer Medical Research Institute, Brisbane, Australia

3. Clinical Tropical Medicine, QIMR-Berghofer Medical Research Institute, Brisbane, Australia

4. Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

Abstract

The South Pacific countries Solomon Islands, Vanuatu, and Papua New Guinea (PNG) adopted artemisinin-based combination therapies (ACTs) in 2008. We examined Kelch 13 and Kelch 12 genes in parasites originating from these countries before or at ACT introduction.

Funder

DOD | Defense Health Agency

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference58 articles.

1. WHO. 2018. World malaria report 2018. World Health Organization, Geneva, Switzerland.

2. WHO. 2006. Guidelines for the treatment of malaria. World Health Organization, Geneva, Switzerland.

3. Evidence of Artemisinin-Resistant Malaria in Western Cambodia

4. Artemisinin Resistance inPlasmodium falciparumMalaria

5. Emerging artemisinin resistance in the border areas of Thailand

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3