Product of Staphylococcus aureus Responsible for the Scalded-Skin Syndrome

Author:

Kapral F. A.1,Miller Margaret M.1

Affiliation:

1. Department of Medical Microbiology, Ohio State University, Columbus Ohio, 43210

Abstract

Certain Staphylococcus aureus strains of phage group 2 produced a protein distinct from the alpha and delta toxins which was capable of causing generalized exfoliation in neonatal mice and presumably is responsible for the scalded-skin syndrome in humans. This protein, named “exfoliatin,” was purified and found to have a molecular weight of approximately 24,000. Exfoliatin was acid-labile, rather heat-stabile, and antigenic.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference10 articles.

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