Agglutinating monoclonal antibodies that specifically recognize lipooligosaccharide A of Bordetella pertussis

Author:

Li Z M1,Cowell J L1,Brennan M J1,Burns D L1,Manclark C R1

Affiliation:

1. Division of Bacterial Products, Food and Drug Administration, Bethesda, Maryland 20892.

Abstract

Monoclonal antibodies that specifically agglutinate strains of Bordetella pertussis having serotype 1 agglutinogen were uniquely reactive with the electrophoretically slow-migrating A form of lipooligosaccharide. These monoclonal antibodies should be useful for the structural analysis of B. pertussis lipooligosaccharide and for the establishment of a better-defined serogroup for Bordetella species.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference16 articles.

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