Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells-Reference-Cited by-同舟云学术

Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells

Published:1980-05 Issue:2 Volume:28 Page:464-468
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Kimura L H,Pearsall N N

Abstract

A strong correlation was shown between germination and increased adherence of Candida albicans to human buccal epithelial cells, indicating that germination or other changes in the fungi accompanying germination were responsible for enhanced adherence. Partial inhibition of germination by cysteine resulted in a comparably lower adherence. Preferential adherence of germinated fungi occurred in competition assays with nongerminated and germinated fungi. The enhanced adherence to human mucosal cells of germinated C albicans could represent one mechanism contributing to the pathogenicity of the organism.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.28.2.464-468.1980

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