Author:
Ito Y,Aoki H,Kimura Y,Takano M,Maeno K,Shimokata K
Abstract
We succeeded in enumerating interferon-producing cells induced by allogeneic stimulation, and proved that they were indeed T lymphocytes. The peak level of these cells in spleen was attained on day 5 after immunication, was maintained for about 2 days, and declined thereafter. Titers of interferon produced in vitro by sensitized spleen cells were maximum on day 7. This suggests that the maturation of immune interferon-producing cells follows cell proliferation after antigen stimulation.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference5 articles.
1. A plaque assay for enumerating antigen-sensitive cells in delayed hypersensitivity;Bloom B. R.;J. Exp. Med.,1970
2. Immune interferon produced in vitro as a quantitative indicator of cell-mediated immunity;Ito Y.;Microbiol. Immunol.,1979
3. The role of individual spleen cells in the interferon response of the intact mouse;Osborn J. E.;J. Exp. Med.,1969
4. Studies on the pathogenicity of human-origin parainfluenza virus in the brain of mice;Shimokata K.;Microbiol. Immunol.,1978
5. Surface alloantigens of plasma cells;Takahashi T.;J. Exp. Med.,1970
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