Polyclonal activation of human lymphocytes by bacteria

Author:

Räsänen L,Karhumäki E,Majuri R,Arvilommi H

Abstract

The proliferative response of human unseparated lymphocytes, T cells, and B cells to various bacterial strains was investigated. All the bacteria tested induced a proliferative response in unseparated lymphocytes and B cells. T cells were stimulated only after reconstitution with monocytes. Stimulation of umbilical cord blood lymphocytes suggests that the response is polyclonal. We interpret these and previous data as an indication of a common mechanism of resistance against infectious diseases.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference21 articles.

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