ABCDs of the Relative Contributions of Pseudomonas aeruginosa Quorum Sensing Systems to Virulence in Diverse Nonvertebrate Hosts-Reference-Cited by-同舟云学术

ABCDs of the Relative Contributions of Pseudomonas aeruginosa Quorum Sensing Systems to Virulence in Diverse Nonvertebrate Hosts

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Vasquez-Rifo Alejandro¹,Cook Jamie²,McEwan Deborah L.³⁴,Shikara Dania²,Ausubel Frederick M.³⁴,Di Cara Francesca²,Cheng Zhenyu²^ORCID

Affiliation:

1. Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA

2. Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada

3. Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA

4. Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA

Abstract

In this study, we performed a systematic comparison of the virulence of WT P. aeruginosa and QS mutants in selected hosts and conditions. This work represents an important contribution to the long-term goal of unraveling the entangled roles of different branches of the P. aeruginosa QS network in different hosts and will serve as a valuable resource for the field of host-pathogen interactions.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

HHS | National Institutes of Health

HHS | U.S. Public Health Service

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00417-22

Reference24 articles.

1. The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes