Listeria monocytogenes TcyKLMN Cystine/Cysteine Transporter Facilitates Glutathione Synthesis and Virulence Gene Expression-Reference-Cited by-同舟云学术

Listeria monocytogenes TcyKLMN Cystine/Cysteine Transporter Facilitates Glutathione Synthesis and Virulence Gene Expression

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Brenner Moran¹,Friedman Sivan¹,Haber Adi²,Livnat-Levanon Nurit²,Borovok Ilya¹,Sigal Nadejda¹,Lewinson Oded²,Herskovits Anat A.¹^ORCID

Affiliation:

1. The Shmunis School of Biomedicine and Cancer Research, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel

2. Department of Biochemistry, The Bruce and Ruth Rappaport Faculty of Medicine, The Rappaport Institute for Biomedical research, Technion—Israel Institute of Technology, Haifa, Israel

Abstract

Bacterial pathogens sense the repertoire of metabolites in the mammalian niche and use this information to shift into the pathogenic state to accomplish a successful infection. Glutathione is a virulence-activating signal that is synthesized by L. monocytogenes during infection of mammalian cells.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00448-22

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