The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection-Reference-Cited by-同舟云学术

The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Roberts Adam¹²,Nagar Rupa³,Brandt Cordelia⁴,Harcourt Katherine⁴,Clare Simon⁴,Ferguson Michael A. J.³,Wright Gavin J.¹²^ORCID

Affiliation:

1. Cell Surface Signalling Laboratory, Wellcome Sanger Institute, Hinxton, Cambridge, United Kingdom

2. Department of Biology, Hull York Medical School, York Biomedical Research Institute, University of York, York, United Kingdom

3. Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom

4. Pathogen Support Team, Wellcome Sanger Institute, Hinxton, Cambridge, United Kingdom

Abstract

Visceral leishmaniasis is a deadly infectious disease caused by the parasitesLeishmania donovaniandLeishmania infantum. It remains a major global health problem, and there is no licensed highly effective vaccine.

Funder

Wellcome

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00433-22

Reference70 articles.

1. WHO. 2021. Leishmaniasis fact sheet. WHO fact sheet.

2. Leishmaniasis in high-burden countries: an epidemiological update based on data reported in 2014;WHO;Wkly Epidemiol Rec,2016

3. Review of the current treatments for leishmaniases

4. Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India

5. Drug Resistance in Leishmaniasis

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases;International Journal of Molecular Sciences;2024-05-11

2. Prospects and Challenges of Genetically Modified Live-Attenuated Leishmania Vaccines;Zoonoses;2024

3. Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania;Microorganisms;2023-04-16

4. The endoplasmic reticulum of trypanosomatids: An unrevealed road for chemotherapy;Frontiers in Cellular and Infection Microbiology;2022-11-10